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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AVPR2 All Species: 15.15
Human Site: S363 Identified Species: 37.04
UniProt: P30518 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P30518 NP_000045.1 371 40279 S363 E S C T T A S S S L A K D T S
Chimpanzee Pan troglodytes XP_525039 424 47111 H376 D G S L S S R H T T L L T R S
Rhesus Macaque Macaca mulatta P56494 389 42895 N367 T S T S K K S N S S S F V L S
Dog Lupus familis XP_545695 420 46143 T376 S P S S R R T T L L T R S S G
Cat Felis silvestris
Mouse Mus musculus O88721 371 40627 S363 E S C A T A S S S L M K D T P
Rat Rattus norvegicus Q00788 371 40730 S363 E S C A T A S S S L M K D T P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520272 381 41874 S373 D S C A T A T S S L A K E I H
Chicken Gallus gallus NP_001026650 370 42416 D349 E N T S A Q E D S V V T G S I
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001921565 389 44223 L337 T M V S S L Y L S F K S H S D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q868T3 506 55785 T463 R T L T T S L T V S R R S T N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 41.2 41.6 40.7 N.A. 87.5 87.8 N.A. 65.8 40.4 N.A. 43.1 N.A. 24.7 N.A. N.A. N.A.
Protein Similarity: 100 53.5 58.3 54.7 N.A. 89.7 89.7 N.A. 73.2 58.7 N.A. 58 N.A. 40.5 N.A. N.A. N.A.
P-Site Identity: 100 6.6 26.6 6.6 N.A. 80 80 N.A. 60 13.3 N.A. 6.6 N.A. 20 N.A. N.A. N.A.
P-Site Similarity: 100 33.3 46.6 40 N.A. 80 80 N.A. 80 40 N.A. 26.6 N.A. 53.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 30 10 40 0 0 0 0 20 0 0 0 0 % A
% Cys: 0 0 40 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 20 0 0 0 0 0 0 10 0 0 0 0 30 0 10 % D
% Glu: 40 0 0 0 0 0 10 0 0 0 0 0 10 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 10 0 10 0 0 0 % F
% Gly: 0 10 0 0 0 0 0 0 0 0 0 0 10 0 10 % G
% His: 0 0 0 0 0 0 0 10 0 0 0 0 10 0 10 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 10 % I
% Lys: 0 0 0 0 10 10 0 0 0 0 10 40 0 0 0 % K
% Leu: 0 0 10 10 0 10 10 10 10 50 10 10 0 10 0 % L
% Met: 0 10 0 0 0 0 0 0 0 0 20 0 0 0 0 % M
% Asn: 0 10 0 0 0 0 0 10 0 0 0 0 0 0 10 % N
% Pro: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 20 % P
% Gln: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % Q
% Arg: 10 0 0 0 10 10 10 0 0 0 10 20 0 10 0 % R
% Ser: 10 50 20 40 20 20 40 40 70 20 10 10 20 30 30 % S
% Thr: 20 10 20 20 50 0 20 20 10 10 10 10 10 40 0 % T
% Val: 0 0 10 0 0 0 0 0 10 10 10 0 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _